Orforglipron and pregnancy: safety, planning, breastfeeding
Orforglipron · orforglipron · by Eli Lilly
Reviewed by the glpzoom Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.
Content current as of June 2026; updated when guidance or availability changes.
Not recommended in pregnancy (GLP-1 class). Discontinue before planned conception; discuss timing with your prescriber.
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Frequently asked
Can I take Orforglipron while pregnant?+
Not recommended in pregnancy (GLP-1 class). Discontinue before planned conception; discuss timing with your prescriber.
How long before pregnancy should I stop Orforglipron?+
Manufacturer guidance typically recommends a 1-2 month washout before planned conception. Confirm timing with your prescriber.
Can I breastfeed while on Orforglipron?+
Orforglipron is not recommended while breastfeeding. Discuss alternative options with your clinician.