Alternatives — drug-by-drug and brand-by-brand
When the drug or telehealth program you started with stops working — due to coverage changes, tolerance, plateau, cost, or preference — here are editorially-reviewed alternatives organized by intent. Each comparison shows "best for" use case and FDA indication match type.
Drug alternatives
Compare alternatives to a specific medication — including same-mechanism, cross-mechanism, and indication-shift options.
Wegovy alternatives
semaglutide · 4 options compared
Most common reasons: insurance denied Wegovy, intolerable nausea, plateau at maintenance dose, or seeking lower cost. Each alternative below addresses…
Zepbound alternatives
tirzepatide · 4 options compared
Common reasons: insurance excludes Zepbound, GI side effects too severe, looking for cheaper self-pay options, or wanting a drug with longer real-worl…
Ozempic alternatives
semaglutide · 4 options compared
Common reasons: shortage (less common now), insurance denied off-label weight-loss use, looking for higher weight-loss potency, or transitioning to ob…
Mounjaro alternatives
tirzepatide · 3 options compared
Common reasons: prescription transition between T2D and obesity indication, side-effect tolerance issues, insurance formulary changes, or looking for …
Saxenda alternatives
liraglutide · 3 options compared
Common reasons: tired of daily injections, want greater weight-loss potency, insurance changes, or anticipating generic liraglutide arrival.…
Viagra alternatives
sildenafil · 1 options compared
Common reasons: cost (generic sildenafil dramatically cheaper), prefer longer-acting option, side-effect intolerance (headache, flushing), or want non…
Cialis alternatives
tadalafil · 1 options compared
Common reasons: cost (generic tadalafil), shorter onset desired, side-effect tolerance, or preference for on-demand vs daily dosing.…
Brand alternatives
Looking for alternatives to a specific telehealth program (Hers, Ro, Sequence, etc.)? Browse alternatives by brand.
Related comparison formats
Why trust this comparison? 5-factor methodology · editorial policy · affiliate disclosure