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Ozempic dosage chart and titration schedule

Ozempic · semaglutide · by Novo Nordisk

Reviewed by the WeighedHealth Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.
Content current as of July 2026; updated when guidance or availability changes.
0.25mg weekly for 4 weeks, then 0.5mg, then 1mg, max 2mg. Lower max dose than Wegovy (2.4mg).

Ozempic dosage chart

Once-weekly subcutaneous injection (type 2 diabetes)

WhenDoseNotes
Weeks 1-40.25 mg once weeklyStarting dose — titration only
Week 5 onward0.5 mg once weeklyFirst maintenance option
After ≥4 weeks at 0.5 mg1 mg once weeklyIf more control needed
After ≥4 weeks at 1 mg2 mg once weeklyMaximum dose

Maintenance: Maintenance is 0.5 mg, 1 mg, or 2 mg once weekly depending on glycemic response and tolerability. The 0.25 mg starting dose is for titration only.

Standard schedule from the FDA Ozempic prescribing information. A prescriber may hold or slow a step for tolerability; do not adjust your dose without clinical guidance.

Where to get Ozempic

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More on Ozempic

People also ask

Frequently asked

What is the standard Ozempic titration schedule?+

0.25mg weekly for 4 weeks, then 0.5mg, then 1mg, max 2mg. Lower max dose than Wegovy (2.4mg).

What if I miss a Ozempic dose?+

Missed-dose guidance depends on time elapsed since the scheduled injection. As a general rule, take the missed dose within the manufacturer's recovery window; if past that, skip and resume the regular schedule. Confirm with prescribing clinician.

Get Ozempic via Rofrom $145/mo