Can I take Wegovy with metformin?

Yes — Wegovy and metformin are commonly used together, particularly in patients with type 2 diabetes who are also pursuing weight loss. The two medications work through different mechanisms (Wegovy mimics GLP-1; metformin improves insulin sensitivity and reduces hepatic glucose output), so they're additive rather than redundant. Combined use does not significantly increase hypoglycemia risk because neither medication alone causes hypoglycemia in normal patients; risk emerges only when combined with insulin or sulfonylureas. GI side effects can be additive — both medications can cause nausea, diarrhea, and abdominal discomfort. Starting Wegovy while already on metformin (or adding metformin to a stable Wegovy regimen) should be done with close monitoring of GI tolerance. Talk to your prescriber about timing — some patients find taking metformin with food and Wegovy on an empty stomach minimizes overlap.