How do I store Zepbound?
Reviewed by the glpzoom Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.
Content current as of June 2026; updated when guidance or availability changes.
Unused Zepbound pens: refrigerate at 36-46°F (2-8°C). Don't freeze. Once in use, Zepbound pens can be kept at room temperature (up to 86°F / 30°C) or refrigerated for up to 21 days. Zepbound vials (used in the LillyDirect direct-pay program) have similar requirements — refrigerate unused, can be at room temperature once opened for 21 days, then discard. For travel: original packaging, carry-on only, insulated bag with ice pack for trips >4 hours. Don't expose to direct sunlight. If a pen or vial is accidentally frozen or exposed to >86°F, discard. The 21-day room-temp limit is shorter than Wegovy's 28 days — note the difference if switching brands.
Where to start
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Ro
from $145/mo- Best for insured patients
- Best for clinical oversight
Ro Body — branded GLP-1 weight care program
Hims
from $199/mo- Best for cash-pay
- Best for speed
Hims Weight Loss — compounded GLP-1 from $199/mo
Drugs referenced
Related questions
How do I store Wegovy?
Unused: refrigerate 36-46°F, never freeze. In use: room temp up to 28 days, then discard. Travel: original packaging, carry-on only (not checked), insulated bag with ice for trips >4 hours.