How much does Zepbound cost?

Zepbound's list price is roughly $1,060 per 28-day supply at retail pharmacies. Eli Lilly runs LillyDirect Self-Pay, which offers vials at $299 (2.5 mg), $399 (5 mg), and $449 (7.5-15 mg) per month when refilled within 45 days, or $499-$699 for 7.5-15 mg otherwise. The Zepbound savings card applies to the single-dose pen instead. Commercial insurance coverag

How much does Wegovy cost without insurance?

Without insurance, Wegovy's list price is approximately $1,349 per 28-day supply, regardless of dose. Novo Nordisk runs a self-pay program (NovoCare) that lowers the cost to $349/month, with no insurance required (new patients pay $199/month for the first two fills of 0.25 mg and 0.5 mg through December 31, 2026). The Wegovy pill is $149-299/month by dose. S

Is Wegovy or Zepbound cheaper?

Reviewed by the WeighedHealth Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.

Content current as of July 2026; updated when guidance or availability changes.

At list price, Zepbound is slightly cheaper than Wegovy (~$1,060 vs ~$1,349/month). For cash-pay patients, Lilly's self-pay vials ($299-$449/month for Zepbound when refilled within 45 days) compare with Novo's NovoCare self-pay ($349/month for Wegovy pens). The 2.5 mg Zepbound vial is cheaper; from 5 mg up the vials cost more than Wegovy self-pay. Insurance coverage patterns are similar; the better choice for any individual depends on which drug their formulary covers preferentially.

Where to start

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Is Wegovy or Zepbound cheaper?

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