Aldactone spironolactone

Face SkincareBy Multiple· FDA-approved 1960

Oral anti-androgen for adult female hormonal acne. 50-100mg daily.

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Reviewed by the glpzoom Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.

Content current as of June 2026; updated when guidance or availability changes.

What is Aldactone?

Originally a potassium-sparing diuretic for high blood pressure and heart failure. Used off-label for adult female hormonal acne and hirsutism (excess facial/body hair).

How does Aldactone work?

Blocks androgen receptors in skin (reduces hormonal acne) and in hair follicles (reduces unwanted hair growth). Takes 3 months for full effect.

Who can take Aldactone?

Adult women with hormonal acne (jawline, chin, around-menstruation flares). Not appropriate for men (causes breast tissue growth). Requires periodic potassium and creatinine monitoring.

How is Aldactone taken?

Start 25-50mg daily, titrate to 50-100mg based on response. Sometimes paired with oral contraceptives for synergy.

How much does Aldactone cost?

$10-25/month generic. Via telehealth dermatology: $30-50/month bundled with consultation.

What side effects can Aldactone cause?

Increased urination, low blood pressure, breast tenderness, irregular menstrual cycles. High potassium (rare, monitored via labs). Discontinue if pregnant — risk of feminization of male fetus.

What if I miss a dose of Aldactone?

Spironolactone is dosed once or twice daily. If missed: take when remembered if within a few hours, or skip and resume regular schedule. Do not double up — increases risk of hypotension and hyperkalemia. Consistency matters for steady hormonal effect.

Where to get Aldactone

Licensed US telehealth providers that prescribe/ship Aldactone. We earn commission when you book. See disclosure.

Curology
from $20/mo
Curology — prescription-strength formula made for your skin
Off-Rx: no plan
Flaws but not dealbreakers (2)
- Providers are usually mid-level (PA/NP) not MD/DO dermatologists
- Less specialized than Apostrophe for complex skin
Visit Curology →Read review
We may earn a commission. Pricing on partner site is final.
Apostrophe
from $20/mo
Apostrophe — board-certified dermatologists prescribe online
Off-Rx: no plan
Flaws but not dealbreakers (2)
- Higher per-visit cost than Curology
- No free trial
Visit Apostrophe →Read review
We may earn a commission. Pricing on partner site is final.

Not sure which Aldactone program fits?

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Acne
Anti-aging
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How to get it

Take the eligibility quiz
5 minutes of medical-history questions matched to the medication's FDA criteria. Free, no commitment.
Submit ID + a recent photo
Required by every legitimate US telehealth platform to verify identity and meet state prescribing rules.
Async clinical review
A licensed clinician in your state reviews your history and decides whether the medication is appropriate. Typically within 24-48 hours.
Prescription ships
If approved, the medication is sent from a partner pharmacy. Initial titration dose arrives in 3-7 days for most US states.
Ongoing support
Most programs include follow-up check-ins, dose adjustments, and side-effect support. Coverage varies by program.

Sources

Primary references this page draws from. We cite original sources so you can verify any claim.

Other face skincare medications

skincare

Retin-A

tretinoin · FDA 1971 · Prescription-strength vitamin A derivative. Gold standard for acne and photoaging.

More on Aldactone

For clinicians: see the Aldactone prescribing summary.