Lilly direct-selling Zepbound at $499/mo — compare with 11 other programs

How much does Zepbound cost?

Zepbound · tirzepatide · by Eli Lilly

Reviewed by the glpzoom Editorial Team against primary clinical sources — FDA labeling, peer-reviewed trials, and specialty-society guidelines.
Content current as of June 2026; updated when guidance or availability changes.
List price ~$1,000-1,300/month. Lilly's patient assistance program (LillyDirect Self-Pay) offers $399-549/month for self-pay patients depending on dose. Insurance coverage similar pattern to Wegovy.

Zepbound pharmacy prices

Updated 1mo agoRefreshed 2026-05-01
Lowest reference price: $349/mo via LillyDirect

Reference monthly prices (28-day supply). Real pricing varies by zip code, dose, and changes frequently. Always check live coupons before purchase.

PharmacyMonthlyTypeNotes
LillyDirect$349Lowestmanufacturer · self-payLillyDirect Self-Pay vials, 2.5mg dose. 7.5-15mg doses run $499-$549/mo.
Costco Pharmacy$1,035warehouseMember cash price
GoodRx coupon$1,050discount-card · couponLimited GoodRx discount on branded Zepbound
CVS Pharmacy$1,060retailLargest US retail pharmacy chain. Brand-name list price typical.
Walgreens$1,060retailSecond-largest US retail pharmacy. Brand-name pricing in line with industry list.
Walmart Pharmacy$1,060warehouseBig-box pharmacy with $4 generic program. Brand prescription pricing closer to retail.
Amazon Pharmacy$1,060onlineOnline pharmacy with Prime member discounts on select medications.

Coupon and self-pay eligibility apply. Check each program's terms. Manufacturer self-pay programs (NovoCare, LillyDirect) typically require no commercial insurance coverage of the drug for eligibility.

Where to get Zepbound

  • Ro logo

    Ro

    from $145/mo
    • Best for insured patients
    • Best for clinical oversight

    Ro Body — branded GLP-1 weight care program

  • Hims logo

    Hims

    from $199/mo
    • Best for cash-pay
    • Best for speed

    Hims Weight Loss — compounded GLP-1 from $199/mo

More on Zepbound

People also ask

Frequently asked

How much does Zepbound cost without insurance?+

List price ~$1,000-1,300/month. Lilly's patient assistance program (LillyDirect Self-Pay) offers $399-549/month for self-pay patients depending on dose. Insurance coverage similar pattern to Wegovy.

Does insurance cover Zepbound?+

Insurance coverage for Zepbound varies by carrier and plan. Most plans require prior authorization and a documented medical indication. Cash-pay alternatives and manufacturer savings programs are often more predictable.

Is there a generic version of Zepbound?+

Not at standard pharmacies. tirzepatide is the active ingredient; compounded versions are sometimes prescribed via telehealth, but their legal status changes as supply normalizes.

Get Zepbound via Rofrom $145/mo
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